Degrading mutations
نویسندگان
چکیده
منابع مشابه
[Glucagon degrading activity].
To evaluate the effect of glucagon degrading activity (GDA) on radioimmunoassay (RIA) of glucagon, I measured GDAs in plasma, serum, lysed red blood cells (RBC), and suspension of mononuclear cells and granulocytes. Serum levels of GDA in patients with various diseases were also examined. 1. Serum GDA values in normal subjects (control) measured by TCA precipitation method were 4.6 +/- 2.2% (me...
متن کاملLignin-degrading enzymes
The substantial potential applications of lignin-degrading microbes and enzymes have spurred research on lignin biodegradation in recent years. As described here, that research has led to the discovery in the basidiomycete Phanerochaete chrysosporium of the first lignin-degrading enzymes and elucidation of their mode of action. A family of powerful extracellular peroxidase isoenzymes has been t...
متن کاملMutations in a zinc-binding domain of human insulin-degrading enzyme eliminate catalytic activity but not insulin binding.
Insulin-degrading enzyme is a nonlysosomal metalloprotease that initiates degradation of internalized insulin in some cells. We previously identified a potential catalytic site containing an inversion of the Zn(2+)-binding domain of the thermolysin family (Kuo, W.-L., Gehm, B. D., and Rosner, M. R. (1991) Mol. Endocrinol. 4, 1580-1591). The role of this site in catalysis was examined by mutatin...
متن کاملNovel marine carbazole-degrading bacteria.
Eleven carbazole (CAR)-degrading bacterial strains were isolated from seawater collected off the coast of Japan using two different media. Seven isolates were shown to be most closely related to the genera Erythrobacter, Hyphomonas, Sphingosinicella, Caulobacter, and Lysobacter. Meanwhile, strains OC3, OC6S, OC9, and OC11S showed low similarity to known bacteria, the closest relative being Kord...
متن کاملXylan-Degrading Catalytic Flagellar Nanorods.
Flagellin, the main component of flagellar filaments, is a protein possessing polymerization ability. In this work, a novel fusion construct of xylanase A from B. subtilis and Salmonella flagellin was created which is applicable to build xylan-degrading catalytic nanorods of high stability. The FliC-XynA chimera when overexpressed in a flagellin deficient Salmonella host strain was secreted int...
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ژورنال
عنوان ژورنال: Genome Biology
سال: 2001
ISSN: 1465-6906
DOI: 10.1186/gb-spotlight-20010702-01